AUTOMATED ALPHA PARTICLE IRRADIATOR- BIOALPHA

Bio--alpha is the first indigenous computer controlled Alpha Particle Irradiator for alpha irradiation of biological/non-biological samples.  A special assembly is required for alpha irradiation of biological samples due to very low range of alpha travel in air and samples need to be irradiated only at atmospheric/physiological conditions.

A controlled, collimated and uniform alpha radiation can be achieved using Bio-alpha due to its innovative design. The system is designed to irradiate adherent mammalian cell cultures. However, in principle, the system can be used to irradiate any material/samples (biological/non-biological) with defined time/dose of alpha radiation, which are placed in a layer (thickness range should be below the penetration of alpha particles in the sample).

ADVANTAGES

• Computer controlled automated mechanical system.
• Uniform and collimated exposure of alpha radiation to cells in culture condition.
• Variable speed of source and collimator movement with independent control.
• Auto and Manual mode of operation.
• High-precision electronic shutter control through computer to irradiate samples  1 sec to 99 min.

APPLICATION

• High LET Radiation Biology for mammalian cells, microbes and plant cells. A thin section of tissue or organisms of very low thickness could be irradiated using the system with proper optimizing irradiation/incubation conditions and dosimetry.
• Radiation Induced Bystander Effect studies.
• Low dose/fluence radiation biology studies.